Nightmares and hallucinations with aprepitant and opium powder: a suspected drug –drug interaction

We describe a strongly suspected elderly cancer patient's DDI between aprepitant and opium powder in the context of an irinotecan‐based regimen manifested by nightmares and visual hallucinations. We discuss this DDI's hypothetical pharmacological mech anisms and management.

Source: British Journal of Clinical Pharmacology - November 26, 2018 Category: Drugs & Pharmacology Authors: Gr égoire Narjoux, Justine Clarenne, Brahim Azzouz, Pauline‐Saraï Zeller, Florian Slimano, Olivier Bouché Tags: CASE REPORT Source Type: research