Acetaminophen pharmacokinetics in severely obese adolescents and young adults
ConclusionCurrent recommendations of acetaminophen to a maximum dose of 1000 mg resulted in serum concentrations below detection limits in all patients within 2 hours after administration. Dose is better predicted using total body mass with allometric scaling.
Risk Factors for Moderate to Severe Pain during the First 24 Hours after Laparoscopic Bariatric Surgery While Receiving Intravenous Patient-Controlled Analgesia. Anesthesiol Res Pract. 2019;2019:6593736 Authors: Iamaroon A, Tangwiwat S, Nivatpumin P, Lertwacha T, Rungmongkolsab P, Pangthipampai P Abstract Objective: To investigate the incidence of and risk factors for moderate to severe pain during the first 24 hours after laparoscopic bariatric surgery. Materials and Methods: This retrospective study included morbidly obese patients who underwent laparoscopic sleeve gastrectomy or Ro...
The laparoscopic adjustable gastric band (AGB) is associated with poor long-term weight loss and frequent untoward outcomes. Increasingly, patients are referred for revisional bariatric surgery, wherein a previously-placed adjustable gastric band is removed in favor of laparoscopic Roux-en-Y gastric bypass or sleeve gastrectomy (SG). Recently, data have emerged that argue for the safety of a 1-stage approach to these maneuvers, which offers potential benefits over a 2-stage approach including fewer instances of general anesthesia, fewer total abdominal procedures, and fewer interruptions in patients ’ lives.
We report the Results of an RCT testing an ERAS protocol incorporating a novel multidrug strategy in patients undergoing laparoscopic sleeve gastrectomy (LSG).
AbstractBackgroundDexmedetomidine is an α2 receptor agonist with sedative and analgesic properties. During bariatric surgery, its use may reduce postoperative opioid requirements, reduce their side effects, and improve quality of recovery.The aim of this prospective randomized controlled trial was to compare the effect of dexmedetomidine bolus and infusion versus morphine bolus given prior to the end of laparoscopic bariatric surgery.MethodsSixty morbidly obese patients (BMI > 40 kg m−2) aged 18 to 60 years, undergoing laparoscopic sleeve gastrectomy, received morphine sulfate...
CONCLUSIONS: We found no significant differences between the 2 anesthetic regimens regarding postoperative nausea and pain, awakening time, peritoneal stretch, or the use of perioperative muscle relaxants. PMID: 31227317 [PubMed - as supplied by publisher]
Conclusions: Low-flow anesthesia is safe regarding hemodynamic and respiratory characteristics, depth of anesthesia, and regional cerebral oxygen saturation in morbidly obese patients undergoing laparoscopic bariatric surgery. PMID: 30766625 [PubMed]
ConclusionsThe severity and incidence of PONV are similar following SG and GB. Importantly, there was no difference in hospital utilization due to PONV between SG and GB.
CONCLUSION: Current recommendations of acetaminophen to a maximum dose of 1000 mg resulted in serum concentrations below detection limits in all patients within 2 hours after administration. Dose is better predicted using total body mass with allometric scaling. PMID: 30484909 [PubMed - as supplied by publisher]
We present two clinical cases of major laparoscopic abdominal surgery combined with plastic surgery after the first intervention of bariatric surgery.
Conclusion: We detected no significant difference in the duration of operation and intra- or postoperative complication between SMO and MO groups. The possibility of the safety of this procedure in SMO group can be adopted.