Fetal fraction ‐based risk algorithm for non‐invasive prenatal testing: screening for trisomies 13 and 18 and triploidy in women with low cell‐free fetal DNA

ConclusionsFor pregnancies with a FF too low to receive a result on standard NIPT, the FFBR algorithm identified a subset of cases at increased risk for trisomy 13, trisomy 18 or triploidy. For the remainder of cases, the risk of a fetal chromosomal abnormality was unchanged from that expected based on MA and GA. © 2018 The Authors.Ultrasound in Obstetrics& Gynecology published by John Wiley& Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

https://onlinelibrary.wiley.com/doi/abs/10.1002/uog.19176?af=R

Source: Ultrasound in Obstetrics and Gynecology - November 26, 2018 Category: Radiology Authors: T. McKanna, A. Ryan, S. Krinshpun, S. Kareht, K. Marchand, C. Grabarits, M. Ali, A. McElheny, K. Gardiner, K. LeChien, M. Hsu, D. Saltzman, M. Stosic, K. Martin, P. Benn Tags: Original Paper Source Type: research