MRI Outperforms [18F]AV ‐1451 PET as a Longitudinal Biomarker in Progressive Supranuclear Palsy

Conclusions: [18F]AV ‐1451 tau‐PET measures increase over time in subjects with PSP, but longitudinal [18F]AV ‐1451 measures may not perform as well as rate of midbrain atrophy as biomarkers for PSP clinical trials. © 2018 International Parkinson and Movement Disorder Society

Source: Movement Disorders - November 23, 2018 Category: Neurology Authors: Jennifer L. Whitwell, Nirubol Tosakulwong, Christopher G. Schwarz, Hugo Botha, Matthew L. Senjem, Anthony J. Spychalla, J. Eric Ahlskog, David S. Knopman, Ronald C. Petersen, Clifford R. Jack, Val J. Lowe, Keith A. Josephs Tags: Research Article Source Type: research