Antibiotics could extend your life by culling older cells that can no longer divide

Salford University scientists made the discovery using azithromycin, which treats infections ranging from gonorrhoea to Lyme disease.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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LYME disease is a relatively unknown condition with an estimated 2,000 to 3,000 new cases each year in England and Wales. For an unknown disease however, anyone can develop the condition as its caught by a tick. This major symptom could mean you might have Lyme disease. Do you have it?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Expression of NF-κB in juvenile rats with nephrotic syndrome and its effects on inflammatory changes and renal injury. Eur Rev Med Pharmacol Sci. 2019 May;23(9):4010-4016 Authors: Sun XM, Sun XH, Li ZY, Yuan CJ, Wu J Abstract OBJECTIVE: The aim of this study was to investigate the expression of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) in juvenile rats with nephrotic syndrome, and to explore its effects on inflammatory changes and renal injury. MATERIALS AND METHODS: 24 Sprague-Dawley (SD) rats were randomly divided into the normal group (n=12) and model gro...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Gentamicin is no more effective overall than ceftriaxone as a first-line treatment for gonorrhoea but could be a useful alternative for some patients, researchers have said.
Source: Clinical Pharmacist - Category: Drugs & Pharmacology Source Type: research
The Russian Gonococcal Antimicrobial Surveillance Programme (RU-GASP) was established in 2004 and operated continuously during the years from 2005 to 2016. The aims of this study were to summarize the RU-GASP results over this 12-year period and evaluate the trends in Neisseria gonorrhoeae antimicrobial resistance in Russia. In total, 5,038 verified N. gonorrhoeae isolates from 40 participating regions were tested for susceptibility to six antimicrobials via an agar dilution method. DNA loci involved in antimicrobial resistance were identified via minisequencing or DNA microarray techniques. From 2005 to 2016, increasing s...
Source: Journal of Clinical Microbiology - Category: Microbiology Authors: Tags: Epidemiology Source Type: research
Researchers at the University of Connecticut have developed a 3D printed enzyme-linked immunosorbent assay (ELISA) device, which fits onto a normal pipette and substantially reduces the time and cost of this common medical test. The device could allo...
Source: Medgadget - Category: Medical Devices Authors: Tags: Genetics Materials Medicine Pathology Source Type: blogs
Condition:   Gonorrhea Interventions:   Drug: zoliflodacin;   Drug: ceftriaxone;   Drug: azithromycin Sponsor:   Global Antibiotics Research and Development Partnership Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In conclusion, the cross-resistance with azithromycin indicates that cethromycin may not be considered for empirical first-line monotherapy of gonorrhoea. However, cethromycin might be valuable in combination antimicrobial therapy and for second-line therapy e.g. for cases with ceftriaxone resistance or allergy. PMID: 31106713 [PubMed - as supplied by publisher]
Source: Journal of Chemotherapy - Category: Cancer & Oncology Tags: J Chemother Source Type: research
Salford University scientists made the discovery using azithromycin, which treats infections ranging from gonorrhoea to Lyme disease.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
More News: Azithromycin | Gonorrhoea | Health | Lyme Disease | Zithromax