“Fragile” equilibrium between translation and transcription [Neuroscience]

Loss of fragile X mental retardation protein (FMRP) in fragile X syndrome is the most common cause of inherited intellectual deficiency and is associated with additional neurodevelopmental issues, including increased risks of autism and epilepsy and characteristic physical changes (1). FMRP is an mRNA binding protein (RBP) implicated in many...

Source: Proceedings of the National Academy of Sciences - November 27, 2018 Category: Science Authors: Wayne S. Sossin Tags: Commentaries Source Type: research