Assessment of scatter radiation dose and absorbed doses in eye lens and thyroid gland during digital breast tomosynthesis.

This study aimed to measure scattered dose and estimate organ dose during mammography under conventional (CM) and Tomo (TM) modes in a specific DBT system. Optically stimulated luminescence dosimeters (OSLDs), whose responses were corrected using a parallel-plate ionization chamber, were pasted on the surface of custom-made polymethyl methacrylate (PMMA) and RANDO phantoms to measure entrance surface air kerma (ESAK). ESAK measurements were also acquired with a 4.5-cm thick breast phantom for a standard mammogram. Organ dose conversion factors (CFD ) were determined as ratio of air kerma at a specific depth to that at the surface for the PMMA phantom and multiplied by the ratio of mass energy absorption coefficients of tissue to air. Normalized eye lens and thyroid gland doses were calculated using the RANDO phantom by multiplying CFD and ESAK values. Maximum variability in OSLD response to scatter radiation from the DBT system was 33% in the W/Rh spectrum and variations in scattered dose distribution were observed between CM and TM. The CFD values for eye lens and thyroid gland ranged between 0.58 to 0.66 and 0.29 to 0.33, respectively. Mean organ doses for two-view unilateral imaging were 0.24 (CM) and 0.18 (TM) μGy/mAs for the eye lens and 0.24 (CM) and 0.25 (TM) μGy/mAs for the thyroid gland. Higher organ doses were observed during TM compared to CM as the automatic exposure control (AEC) system resulted in greater total mAs values in TM. PMID: 30472811 [PubMed...
Source: Journal of Applied Clinical Medical Physics - Category: Physics Authors: Tags: J Appl Clin Med Phys Source Type: research

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Health-Related Complications of Acromegaly—Risk of Malignant Neoplasms Marek Ruchala*† and Kosma Wolinski† Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznań, Poland The issue of increased risk of benign and malignant neoplasms in patients with acromegaly remains the topic of debate from many years and was addressed by numerous studies. Many of them have shown increase in the cancer incidence. Among particular types of malignancies, thyroid, colorectal, and breast cancer are most commonly indicated as associated with acromegaly. Single ...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Discussion: Our results demonstrated that cancer risk was not increased in our MS population; but age and sex different distribution may partly drive cancer risk. Higher cancer risk in MS patients switching more than two DMTs should take into account in treatment decision making. Introduction Multiple Sclerosis (MS) is a severe acquired autoimmune neurodegenerative disease of the central nervous system (CNS) with extremely variable disease course, that usually affects persons in their third/four decades of life, even if late onset is described (1). Women had a prevalence/incidence rate approximately double than men (...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
From time to time I have commented on the controversies over cancer screening. Most people assume that screening is an unqualified good, that early detection of cancer saves lives. Whenever some panel proposes recommending less screening, we hear screaming and yelling from advocates who claim they are trying to " ration " health care to save money at the expense of people's lives.In fact,as a bunch of Australians and a Minnesotan explain in BMJ, there are a few conditions called " cancer " that you are better off not treating, or perhaps treating very conservatively. These include what is called ductal ...
Source: Stayin' Alive - Category: American Health Source Type: blogs
The problem of overdiagnosis in cancer screening has been hotly debated for...Read more on AuntMinnie.comRelated Reading: People want cancer screening, despite pitfalls How serious is the risk of breast cancer overdiagnosis? Is the mammography debate an example of 'fake science'? Women still value mammography's benefits over 'harms' Why is thyroid cancer being overdiagnosed in Canada?
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Endomag, a medical technology company based in Cambridge, UK and Austin, Texas, has developed the Magseed, a magnetic injectable marker that can be implanted by a radiologist during an imaging procedure, such as during ultrasound or X-ray mammographi...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Ob/Gyn Pathology Radiology Surgery Source Type: blogs
Recently in JAMA," ...a research letter... explores howsocial interactions with friends, family and colleagues who have been diagnosed with breast cancer may affect a physician ’s recommendations to patients. "What it found was that a doctor's personal experiences impact what they recommend for their patients. They did not necessarily follow the current guidelines. " Physicians familiar with someone with a poor prognosis who was not diagnosed via screening were much more likely to recommend routine checks for women between 40 and 44 years old and those over 75. "“Describing a woman whos...
Source: Caroline's Breast Cancer Blog - Category: Cancer & Oncology Tags: arthritis treatment cancer history cancer screening medical history Source Type: blogs
Conclusion: These data indicate that TBBPA, triclosan, and BPA interact in vivo, consistent with evidence that TBBPA and triclosan inhibit enzymes that are critical for BPA and E2 metabolism. https://doi.org/10.1289/EHP1329 Received: 04 November 2016 Revised: 11 April 2017 Accepted: 13 April 2017 Published: 21 August 2017 Address correspondence to D. deCatanzaro, Dept. of Psychology, Neuroscience &Behaviour, McMaster University, 1280 Main St. West, Hamilton ON L8S 4K1, Canada. Telephone: (905) 525-9140, ext. 23014. Email: decatanz@mcmaster.ca Supplemental Material is available online (https://doi.org/10.1289/EHP1...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
CONCLUSION: Functional thyroid disorders were not related to MD. However, MD was lower in women with goiter and higher in those reporting Hashimoto's thyroiditis. These relationships should be confirmed in future studies. PMID: 28456099 [PubMed - as supplied by publisher]
Source: Breast - Category: Cancer & Oncology Authors: Tags: Breast Source Type: research
Conclusions: With longer follow-up, our rates of local recurrence following breast-conserving therapy for DCIS remain very low (1.5% at 10 years). The vast majority of patients had>2 mm margins, specimen radiographs, and received a tumor bed boost. The majority (60%) of patients with hormone receptor positive disease received adjuvant endocrine therapy. The 10-year incidence of CBC was higher than expected. Predisposing factors for the development of CBC are worthy of investigation.Citation Format: Rattay T, Johnson K, Azria D, Chang-Claude J, Davidson S, Dunning A, de Ruyscher D, Guiterrez-Enriquez S, Lambin P, Rancati...
Source: Cancer Research - Category: Cancer & Oncology Authors: Tags: Poster Session Abstracts Source Type: research
Conclusion We determined that ultrasound findings of round, oval or lobulated shape, accentuating posterior echoes and expansively growing pattern could predict the presence of high TILs. Thus, the safe, low-cost, and radiation-free ultrasound examination was recommended for predicting high TILs and prognosis.Citation Format: Birrell SN, Birrell ND. An open labelled longitudinal evaluation of a subcutaneous combination of testosterone and anastrozole in pre-menopausal women with high volumetric mammographic breast density [abstract]. In: Proceedings of the Thirty-Ninth Annual CTRC-AACR San Antonio Breast Cancer Symposium; ...
Source: Cancer Research - Category: Cancer & Oncology Authors: Tags: Poster Session Abstracts Source Type: research
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