Revisiting the single-energy CT calibration for proton therapy treatment planning: a critical look at the stoichiometric method.
In conclusion, the stoichiometric method for SECT calibration seems to depend on the tissue-substitutes used for calibration-which could be regarded as an additional source of uncertainty in proton range for bone tissues. Furthermore, Gammex tissue-substitutes appear to be a good representative of biological tissues within the energy range relevant to computed tomography-making the stoichiometric method unnecessary.
PMID: 30474618 [PubMed - in process]
Source: Physics in Medicine and Biology - Category: Physics Authors: Gomà C, Almeida IP, Verhaegen F Tags: Phys Med Biol Source Type: research