Severe vemurafenib ‐induced photosensitivity in a 6‐year‐old boy

AbstractVemurafenib, a selective BRAF kinase inhibitor, has been found to induce several cutaneous adverse effects, ranging from a keratosis pilaris ‐like reaction to squamous cell carcinoma. While photosensitivity has been well described as one of these manifestations, we report a case of a 6‐year‐old boy on vemurafenib who developed a severe blistering sunburn after only two 30‐minute episodes of sun exposure. A brief review of other c ommon cutaneous adverse effects of vemurafenib is also provided.
Source: Pediatric Dermatology - Category: Dermatology Authors: Tags: BRIEF REPORT Source Type: research