A Systematic Review and Narrative Synthesis on the histological and neurobehavioral long term effects of dexmedetomidine

ConclusionIn animals, dexmedetomidine was found not to induce histologic injury and to show a beneficial effect when administered with another anesthetic. No clinical results on the long term effects in children have been identified yet.This article is protected by copyright. All rights reserved.
Source: Pediatric Anesthesia - Category: Anesthesiology Authors: Tags: Systematic reviews Source Type: research

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ConclusionSubstantial agreement exists among experts regarding many strong recommendations for the improvement of practice concerning the use of muscle relaxants and reversal agents during anaesthesia. In particular, the French Society of Anaesthesia and Intensive Care (SFAR) recommends the use of a device to monitor neuromuscular blockade throughout anaesthesia.
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
Publication date: January 2020Source: Anaesthesia &Intensive Care Medicine, Volume 21, Issue 1Author(s):
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
Publication date: January 2020Source: Anaesthesia &Intensive Care Medicine, Volume 21, Issue 1Author(s):
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
Conclusion: Activation of NMDAR-NMNAT1/2 signaling pathway could not only reduce neuronal apoptosis, but also alleviate sevoflurane-induced neuronal inflammation and cognitive impairment in aged rats. PMID: 31941414 [PubMed - as supplied by publisher]
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
Some of my colleagues have been avoiding opioids altogether (and using ketamine) for cancer surgery, based on some animal and in-vitro studies showing that opioids may lead to immunosuppression of protective mechanisms and may increase risk of cancer recurrence. From what I've read it is mostly with morphine and there has not been any RCTs performed for this. I haven't jumped on the bandwagon on this. Most of the attendings here like to use remi for head and neck, other surgeries where... avoiding opioid use in cancer surgery
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Anesthesiology Source Type: forums
Can anyone comment on this particular job? Valley Presbyterian in Los angeles? Especially if just doing it for a year. Envision is behind it. Anesthesiologist | Valley Presbyterian Hospital - ANE | Physician Jobs | PracticeMatch.com | 560304 Anesthesiologist | Valley Presbyterian Hospital - ANE | Physician Jobs | PracticeMatch.com | 560304 www.practicematch.com
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Anesthesiology Source Type: forums
ConclusionPilonidal sinus of inframammary region is an extremely rare condition. High index of suspicion is required for diagnosis. Excision with primary closure is the definitive therapy.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
AbstractPurpose of the ReviewThis chapter will highlight several important concepts that are relevant to the assessment and optimization of hospitalized patients prior to the administration of an anesthetic.Recent FindingsPatients admitted to hospital comprise a unique population. The risk-benefit ratio of pre-procedural investigations and the economic implications of specific management strategies may be significantly different than for patients managed on an ambulatory basis. The anesthesiologist must have a thorough understanding of these factors. Preoperative workflows provide effective coordination of the necessary re...
Source: Current Anesthesiology Reports - Category: Anesthesiology Source Type: research
Pethidine has been removed from the South Australian Medicines Formulary due to unfavourable drug properties and its potential to cause adverse maternal and neonatal effects. Traditionally, the opioids most commonly used for labour analgesia were pethidine and morphine.1 However, due to its differing pharmacokinetic profile, fentanyl has been suggested as a suitable alternative to both pethidine and morphine when administered for pain relief during labour. Benefits of fentanyl for labour analgesia include rapid absorption and no active metabolites.
Source: International Journal of Obstetric Anesthesia - Category: Anesthesiology Authors: Tags: Original Article Source Type: research
AbstractPurpose of ReviewPoint-of-care ultrasound (POCUS) has been widely adopted in the management of trauma patients by emergency and surgical specialists. Advances in technology, portability, and affordability have contributed to its exponential growth, particularly in the field of trauma anesthesia where ultrasound usage has steadfastly blossomed in recent years.Recent FindingsStudies and protocols have expanded beyond the oft-used focused assessment with sonography for trauma examination to include focused cardiac and lung examinations. POCUS may also be useful as an adjunct for airway management, vascular access, and...
Source: Current Anesthesiology Reports - Category: Anesthesiology Source Type: research
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