Systematic review of treatment effectiveness and outcome measures for enthesitis in psoriatic arthritis.

Systematic review of treatment effectiveness and outcome measures for enthesitis in psoriatic arthritis.
J Rheumatol. 2014 Nov;41(11):2290-4
Authors: Orbai AM, Weitz J, Siegel EL, Siebert S, Savage LJ, Aydin SZ, Luime JJ, Elkayam O, Neerinckx B, Urbancek S, de Vlam K, Ritchlin CT, GRAPPA Enthesitis Working Group
Abstract
Enthesitis is a characteristic feature of psoriatic arthritis (PsA) and is important in disease pathogenesis and classification. Use of clinical outcome measures for enthesitis is heterogeneous, and only 1 measure has been specifically developed and validated in PsA. Ultrasound and magnetic resonance imaging assessments of enthesitis may have advantages over clinical examination but are insufficiently studied. As part of an update of treatment recommendations by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), we performed a systematic literature review and identified randomized controlled trials with enthesitis outcomes in PsA. For each treatment agent we calculated treatment effect sizes (where applicable) and graded the level of evidence.
PMID: 25362713 [PubMed - in process]

Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Orbai AM, Weitz J, Siegel EL, Siebert S, Savage LJ, Aydin SZ, Luime JJ, Elkayam O, Neerinckx B, Urbancek S, de Vlam K, Ritchlin CT, GRAPPA Enthesitis Working Group Tags: J Rheumatol Source Type: research