Purified ingredient ‐based high‐fat diet is superior to chow‐based equivalent in the induction of metabolic syndrome

In conclusion, purified high‐fat diet is a better diet for MetS induction in rats.Practical applicationsModeling metabolic syndrome is commonly accomplished with the use of chow ‐ or purified ingredient diets enriched with carbohydrates and/or lipids, but the differences and associated drawbacks are unclear. This study highlights that chow‐ or modified chow‐based diets have a tendency to introduce unwanted metabolic changes which are inconsistent with the progression of metabolic syndrome. Thus, the use of these diets in metabolic disease study should be avoided. On the other hand, purified high‐fat diet which can effectively induce the features of metabolic syndrome is highly recommended.
Source: Journal of Food Biochemistry - Category: Food Science Authors: Tags: FULL ARTICLE Source Type: research