Effects of JNJ-40929837, a leukotriene A4 hydrolase inhibitor, in a bronchial allergen challenge model of asthma

In conclusion, JNJ-40929837 demonstrated target engagement in blood and sputum. No significant impact in response to allergen inhalation was observed with JNJ-40929837 versus placebo. Registration This study is registered at ClinicalTrials.gov: NCT01241422.
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research