Radiofrequency spectral analysis of EBUS for peripheral pulmonary lesions

ABSTRACTBackground and objectiveWe previously reported that histogram ‐based quantitative evaluation for endobronchial ultrasonography (EBUS) B‐mode images could differentiate between benign and malignant lesions. However, these images were generated from reconstructed raw radiofrequency (RF) signals and had some limitations. Currently, there are no reports on raw RF signal data to quantitatively differentiate ultrasound information for peripheral pulmonary lesions.MethodsWe prospectively hypothesized that RF spectral analysis from EBUS images could reveal sonographic features of peripheral pulmonary diseases. RF data were imported into a frequency spectral analysis software programme, comparing four parameters: mean frequency (MHz); slope; mid ‐band fit (dB); and y‐intercept (dB), to differentiate between benign and malignant lesions. Furthermore, we compared subgroup analysis within benign and malignant lesions.ResultsRF data from EBUS images were obtained in 146 cases, of which, 106 lung cancers and 40 inflammatory diseases were present. Significant differences were observed for three parameters in benign and malignant lesions (mean frequency:P 
Source: Respirology - Category: Respiratory Medicine Authors: Tags: Original Article Source Type: research

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Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
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Source: The British Journal of Surgery - Category: Surgery Authors: Tags: Br J Surg Source Type: research
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Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
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Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Lung cancer Source Type: research
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Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Thoracic surgery Source Type: research
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Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research
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Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research
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Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research
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Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
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Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
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