Ventral hernia surgery in morbidly obese patients, immediate or after bariatric surgery preparation: Results of a case-matched study

Patients with obesity have a higher incidence of ventral hernias and are at greater risk of developing complications after hernia repair [1,2]. These complications include a higher risk of recurrence, wound infection, wound breakdown, and venous thromboembolic episodes. The elevated intra-abdominal pressure, increased abdominal circumference, and visceral fat may play a role, as might the association of obesity with type 2 diabetes.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Paired editorial Source Type: research

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Authors: Silva MAFS, Dechichi P, Limirio PHJO Abstract Childhood obesity is a considerable worldwide health problem and a major risk factor for several chronic diseases. Fat rich diets result in altered serum levels of lipids, cytokines and hormonal factors, which influence skeletal acquisition and promote microstructural and mechanical behavior changes in bone, especially to bone quality and quantity. However, the possible longterm implications of high-fat diets in childhood are controversial. Despite not fully understood, multiple signaling pathways which support bone tissue homeostasis are altered under hyperlip...
Source: Pediatric Endocrinology Reviews - Category: Endocrinology Tags: Pediatr Endocrinol Rev Source Type: research
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Source: Pediatric Endocrinology Reviews - Category: Endocrinology Tags: Pediatr Endocrinol Rev Source Type: research
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Source: Pediatric Endocrinology Reviews - Category: Endocrinology Tags: Pediatr Endocrinol Rev Source Type: research
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Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Authors: Plunk EC, Richards SM Abstract The epigenome of an individual can be altered by endogenous hormones, environment, age, diet, and exposure to endocrine disrupting chemicals (EDCs), and the effects of these modifications can be seen across generations. Epigenetic modifications to the genome can alter the phenotype of the individual without altering the DNA sequence itself. Epigenetic modifications include DNA methylation, histone modification, and aberrant microRNA (miRNA) expression; they begin during germ cell development and embryogenesis and continue until death. Hormone modulation occurs during the agei...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Authors: Antinozzi C, Sgrò P, Di Luigi L Abstract Among metabolic diseases, carbohydrate metabolism disorders are the most widespread. The most common glucose pathological conditions are acquired and may increase the risk of type 2 diabetes, obesity, heart diseases, stroke, and kidney insufficiency. Phosphodiesterase type 5 inhibitors (PDE5i) have long been used as an effective therapeutic option for the treatment of erectile dysfunction (ED). Different studies have demonstrated that PDE5i, by sensitizing insulin target tissues to insulin, play an important role in controlling the action of insulin and gluco...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
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Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
ConclusionSynchronous VHR and BS in a bariatric unit is feasible with low recurrence rate. Laparoscopic VHR has lower complication rates than open, apart from seroma formation. Patients with diabetes have higher risk of infection.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
Patients with obesity have a higher incidence of ventral hernias and are at greater risk of developing complications after hernia repair (1,2). These include a higher risk of recurrence, wound infection, wound breakdown and venous thromboembolic episodes. The elevated intra-abdominal pressure, increased abdominal circumference and visceral fat may play a role as does the association of obesity with type 2 diabetes.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
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