Infectious Complications in the Outpatient and Inpatient Autologous Stem Cell Transplantation Setting for Patients with Multiple Myeloma. Princess Margaret Cancer Center Experience

Conclusions:In our autotransplant experience, blood stream and lung infections are common, with multi-drug resistance a concern. We were surprised to report that patients undergoing outpatient-based transplant had more BSI, presumably central line-related, and that this may impact disease outcomes (PFS). We hypothesize that outpatients may undergo additional line manipulation or inferior line hygiene, suggesting that enhanced patient/staff education on infection control measures should be a focus. In general, though, outpatient ASCT patients had excellent outcomes, with similar engraftment rates, short readmission rates, low ICU usage, as the entire cohort.DisclosuresTiedemann: Novartis: Consultancy; Celgene: Consultancy; Bristol-Myers Squibb: Consultancy; Janssen: Consultancy; Amgen: Consultancy; Takeda: Consultancy; Merck: Consultancy; Roche: Consultancy. Chen: Amgen: Honoraria.

Source: Blood - November 21, 2018 Category: Hematology Authors: Nikonova, A., Zeglinski, C., Husain, S., So, M., Atenafu, E. G., Reece, D. E., Trudel, S., Kukreti, V., Tiedemann, R. E., Prica, A., Franke, N. A., Huynh, J., Tao, L., Chen, C. I. Tags: 731. Clinical Autologous Transplantation: Results: Poster III Source Type: research