Long-Term Durable Responses after Autologous Stem Cell Transplantation in POEMS Syndrome

Conclusions:Upfront Auto-HCT provides durable chemotherapy free remission and significant clinical improvement in patients with POEMS syndrome.References:Patel, K. et al. Durable responses with autologous hematopoietic SCT in patients with POEMS syndrome. Bone marrow transplantation 49, 465-6 (2014).Figure.DisclosuresThomas: Acerta Pharma: Research Funding; Amgen Inc: Research Funding; Bristol Myers Squibb Inc.: Research Funding; Celgene: Research Funding; Array Pharma: Research Funding. Lee: Celgene: Consultancy, Membership on an entity's Board of Directors or advisory committees; Adaptive Biotechnologies Corporation: Consultancy; Amgen: Consultancy, Membership on an entity's Board of Directors or advisory committees; Chugai Biopharmaceuticals: Consultancy; Takeda Oncology: Consultancy, Membership on an entity's Board of Directors or advisory committees; Kite Pharma: Consultancy, Membership on an entity's Board of Directors or advisory committees. Orlowski: Poseida: Research Funding; Amgen: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding; Genentech: Consultancy; Janssen Pharmaceuticals: Consultancy, Membership on an entity's Board of Directors or advisory committees; BioTheryX, Inc: Consultancy, Membership on an entity's Board of Directors or advisory committees; Bristol Myers Squibb: Consultancy; Celgene: Consultancy, Membership on an entity's Board of Directors or advisory committees; Millenium Pharmaceuticals: Consultancy...

Source: Blood - November 21, 2018 Category: Hematology Authors: Saini, N. Y., Patel, R., Varma, A., Bashir, Q., Hasan, O., Delgado, R., Rondon, G., Mukherjee, A., Popat, U., Hosing, C., Nieto, Y., Kebriaei, P., Weber, D. M., Thomas, S. K., Lee, H. C., Manasanch, E. E., Orlowski, R. Z., Champlin, R. E., Qazilbash, M. H Tags: 731. Clinical Autologous Transplantation: Results: Poster III Source Type: research