Donor Lymphocyte Infusion from G-CSF-Primed, Unmanipulated Whole Blood Is Safe and Improves Chimerism in HLA-Matched and Haploidentical Transplantation

Conclusions: DLI obtained from unmanipulated, GCSF-primed whole-blood is a safe and affordable adoptive cell therapy. It is effective and improves mixed chimerism after HSCT, while it was less effective for overt relapse.DisclosuresGomez-Almaguer: AbbVie: Consultancy; Novartis: Consultancy.

Source: Blood - November 21, 2018 Category: Hematology Authors: Gomez-De Leon, A., Colunga Pedraza, P. R., Garcia-Camarillo, D. E., Vazquez-Garza, R. I., Santana-Hernandez, P., Gutierrez Aguirre, C. H., Cantu Rodriguez, O., Gomez-Almaguer, D. Tags: 723. Clinical Allogeneic and Autologous Transplantation: Late Complications and Approaches to Disease Recurrence: Poster III Source Type: research