Effect of Pulmonary Hypertension and Other Cardiovascular Diseases in Overall Prognosis of Patients with Myelofibrosis

Conclusion:In our cohort of MF, the incidence of pre-capillary PH on echocardiogram was 6%. The presence of AF and echocardiographic findings of left atrial dilatation and decreased RV systolic dysfunction by RVs' are strongly related to worse prognosis. Of which the presence of AF was the most robust. Traditional PH variables in echocardiogram are not related to overall prognosis in this population. Further study is needed to evaluate the impact of cardiovascular disease in MF.Figure.DisclosuresVerstovsek: Celgene: Membership on an entity's Board of Directors or advisory committees; Novartis: Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Italfarmaco: Membership on an entity's Board of Directors or advisory committees; Incyte: Consultancy.

Source: Blood - November 21, 2018 Category: Hematology Authors: Lopez-Mattei, J., Verstovsek, S., Iliescu, C., Bhatti, K., Palaskas, N., Kim, P., Gray, B., Faiz, S. Tags: 634. Myeloproliferative Syndromes: Clinical: Poster III Source Type: research