Outcomes Associated with Therapeutic Anticoagulation in Patients with Brain Metastasis

Conclusion:In this relatively large cohort of patients with brain metastasis, use of therapeutic anticoagulation did not influence the incidence of developing ICH but was associated with a greater risk of clinically significant ICH. This increase was, however, not linked to differences in overall survival. Nearly all patients in our AC cohort were treated with enoxaparin; ongoing studies will examine whether anticoagulation with DOACs is associated with similar outcomes.DisclosuresKhorana: Bayer: Consultancy; Sanofi: Consultancy; Janssen: Consultancy; Pfizer: Consultancy.

Source: Blood - November 21, 2018 Category: Hematology Authors: Rahman, S., Covut, F., Zhou, Y., Rahim, S. E. G., Amarnath, S., Khorana, A. A. Tags: 332. Antithrombotic Therapy: Poster I Source Type: research