Variable Clinical Presentation of Congenital Thrombotic Thrombocytopenic Purpura in a Large Cohort of Patients Carrying a New Mutation in the CUB1 Domain of ADAMTS13 Gene

Conclusion:To the best of our knowledge, this is one of the largest congenital TTP cohorts described in the literature. This cohort is unique due to the fact that all members carry the same, previously unreported, ADAMTS13 gene mutation in the CUB1 domain of the gene. Our findings support an assumption that environmental and hereditary modifiers may influence disease course. Further research of the involved families may enable us to expand the understanding of the pathophysiology and develop better treatment options for this understudied rare condition.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - Category: Hematology Authors: Tags: 311. Disorders of Platelet Number or Function: Poster I Source Type: research

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Mothers going through the hurt and trauma of stillbirth need counselors who recognize the true nature of their loss and are willing to sit with them through their pain rather than rushing them to “move on.” The post Understanding stillbirth appeared first on Counseling Today.
Source: Counseling Today - Category: Psychiatry & Psychology Authors: Tags: Counseling Today Member Insights Couples disenfranchised grief pregnancy women Source Type: research
Journal of Women's Health, Ahead of Print.
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Journal of Women's Health, Ahead of Print.
Source: Journal of Women - Category: OBGYN Authors: Source Type: research
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