External Validation and Revision of Thrombosis Lymphoma /Throly/ Score

ConclusionsRevised Thrombosis Lymphoma - ThroLy score is more specific for lymphoma patients than any other available score targeting thrombosis risk in solid cancer patients. We included biological characteristic of lymphoma, indolent vs aggressive, as well as data about dissemination of disease, localized vs advanced stage, reflecting specificity of lymphomas comparing to other types of cancer. Also, we pointed out significance of central vascular devices as risk factor having considered the role of vascular damage during insertion as a potential trigger for activation of the clotting cascade. This score is user friendly for daily clinical practice and provides a very good predictive power to identify patients who are candidates for pharmacological thromboprophylaxis.DisclosuresCheson: AbbVie, Roche/Genentech, Pharmacyclics, Acerta, TG Therapeutics: Consultancy. Ghielmini: Roche: Consultancy, Honoraria, Research Funding, Speakers Bureau. Jaeger: Gilead: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Novartis: Membership on an entity's Board of Directors or advisory committees, Research Funding; AOP Orphan: Membership on an entity's Board of Directors or advisory committees; Roche: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Janssen: Consultancy,...

Source: Blood - November 21, 2018 Category: Hematology Authors: Antic, D., Milic, N., Mihaljevic, B., Cheson, B., Narkhede, M., Abdel-Razeq, H., Panovska, I., Trajkova, S., Popova, M., Aurer, I., Boban, A., Ghielmini, M., Moccia, A., Delluc, A., Ianotto, J.-C., Jaeger, U., Skrabs, C., Gerotziafas, G. T., Fareed, J. Tags: 331. Pathophysiology of Thrombosis: Cancer- and Children-Associated Thrombosis Source Type: research