A review of the 10/66 dementia research group

DiscussionA body of evidence has been generated that has challenged the view, prevalent when the group started, that dementia is comparatively rare in LMICs. The experience of the 10/66 DRG has shown that descriptive epidemiological research can be important and impactful, where few data exist. Monitoring population trends in the prevalence and incidence of dementia may be our best chance to confirm hypotheses regarding modifiable risk factors of dementia.
Source: Social Psychiatry and Psychiatric Epidemiology - Category: Psychiatry Source Type: research

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Publication date: Available online 22 March 2019Source: The Lancet NeurologyAuthor(s): Daniel Friedman, Jacqueline A French, Mauro MaccarroneSummaryIn the past two decades, there has been an increasing interest in the therapeutic potential of cannabinoids for neurological disorders such as epilepsy, multiple sclerosis, pain, and neurodegenerative diseases. Cannabis-based treatments for pain and spasticity in patients with multiple sclerosis have been approved in some countries. Randomised controlled trials of plant-derived cannabidiol for treatment of Lennox-Gastaut syndrome and Dravet syndrome, two severe childhood-onset ...
Source: The Lancet Neurology - Category: Neurology Source Type: research
[The sleep apnoea syndrome: Clinical characteristics of affected patients in the hospital population of Château-Thierry]. Rev Mal Respir. 2019 Mar 18;: Authors: Goddaert C, Jender A, Zulfiqar AA Abstract INTRODUCTION: The sleep apnoea syndrome (SAS) is a public health problem particularly due to its involvement in cardiovascular and metabolic disorders. The aim of this study was to investigate the epidemiological characteristics of the affected population in order to facilitate screening for SAS. MATERIALS AND METHODS: The study was retrospective, monocentric and observational. It was underta...
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
Publication date: Available online 22 March 2019Source: Journal of Clinical NeuroscienceAuthor(s): Yoon-Jung Kang, Kyung-Hye Kim, Sung-Hwan Jang, Gha-Hyun Lee, Yoon-Jung Lee, Yong-Sun Kim, Eun-Joo KimAbstractThe familial Creutzfeldt-Jakob disease (fCJD) usually has similar clinical and neuroimaging features as sporadic CJD (sCJD). A 57-year-old man presented with a four-month history of rapidly progressive dementia (RPD). Laboratory tests for RPD were all normal. Brain MRI demonstrated diffuse cortical atrophy and no abnormal cortical or striatal hyperintensities on fluid-attenuated inversion recovery (FLAIR)/diffusion wei...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Authors: Bhui K PMID: 30896382 [PubMed - in process]
Source: The British Journal of Psychiatry for Mental Science - Category: Psychiatry Tags: Br J Psychiatry Source Type: research
DISCUSSION: Computerized cognitive training significantly improved global cognitive function, which was supported by the improved brain plasticity. Incorporation of biomarkers should be implemented in cognitive training trials. PMID: 30894299 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
DISCUSSION: These results support the idea of social interaction influencing cognitive outcomes, cognitive training influencing NPS, and both social interaction and cognitive training influencing QoL. The findings illustrate the feasibility and importance of incorporating social activity to computerized cognitive training for people with dementia. CLINICAL IMPLICATIONS: Cognitive training that incorporates social interaction may be a promising intervention for individuals with dementia experiencing NPS. PMID: 30895883 [PubMed - as supplied by publisher]
Source: Clinical Gerontologist - Category: Geriatrics Tags: Clin Gerontol Source Type: research
Authors: Camp CJ Abstract In far too many instances treatment of persons with dementia has reflected a fundamental denial of basic human rights. At times, these individuals are treated worse than the treatment of animals when the five basic freedoms of animals, described by Pachana in her editorial, are implemented. A number of such examples of dehumanizing (and "de-animalizing") persons with dementia are presented. A case is made for the position that this is the direct result of the "medicalization" of dementia and "Alzheimer Disease." This has led to the disenfranchisement of person...
Source: Clinical Gerontologist - Category: Geriatrics Tags: Clin Gerontol Source Type: research
Previous studies have shown that people who are hospitalized for treatment of mental illness have an elevated risk of suicide in the first few months after their discharge. Astudy inPsychiatric Services in Advance now reports that this immediate postdischarge period carries a higher risk not only of suicide, but also of death from other causes such as overdoses, accidents, and injuries. In addition, the findings suggest important opportunities for prevention.Ira R. Katz, M.D., Ph.D., of the Office of Mental Health and Suicide Prevention at the U.S. Department of Veterans Affairs (VA) and colleagues analyzed the records of ...
Source: Psychiatr News - Category: Psychiatry Tags: Ira Katz M.D. natural causes psychiatric hospitalization Psychiatric Services suicide veterans Source Type: research
I was a small piece in the search to find a cure. Now I feel as if I ’ m getting erased, and medical science doesn ’ t have any answers.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Alzheimer's Disease Drugs (Pharmaceuticals) Memory Dementia Clinical Trials Source Type: news
Conclusion: The integrated network pharmacology method provides precise probe to illuminate the molecular mechanisms of the main volatiles of WDG for relieving senile dementia related syndromes, which will also facilitate the application of traditional Chinese medicine as an alternative or supplementary to conventional treatments of AD, as well as follow-up studies such as upgrading the quality standard of clinically applied herbal medicine and novel drug development. PMID: 30891080 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
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