Ligand-Protein Target Screening from Cell Matrices Using Reactive Desorption Electrospray Ionization-Mass Spectrometry via a Native Denatured Exchange Approach

Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01708E, PaperQiuling Zheng, Xujun Ruan, Yang Tian, Jiaojiao Hu, Ning Wan, Wenjie Lu, Xiaowei Xu, Guangji Wang, Haiping Hao, Hui Ye Native mass spectrometry has been recognized as a powerful tool for probing interactions between small molecules, such as drugs and metabolites, and target proteins. However, the presence of heterogeneous proteins... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Analyst latest articles - November 22, 2018 Category: Chemistry Authors: Qiuling Zheng Source Type: research