Calcium-sensing receptor as a therapeutic target for pulmonary fibrosis

Conclusions: Our results are the first to report that functional CaSR is up-regulated in activated lung fibroblasts and that calcilytics reduce markers implicated in pulmonary fibrosis. Thus, CaSR may represent a novel therapeutic target in pulmonary fibrosis.

Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Wolffs, K., Mansfield, B., Scofield, S., Ward, J. P. T., Corrigan, C. J., Prakash, Y. S., Kemp, P. J. K., Riccardi, D. Tags: Idiopathic interstitial pneumonias Source Type: research