Mononuclear phagocytes in lungs, lymph nodes and blood of sarcoidosis patients

Conclusions: We show that cells from BAL fluid do not necessarily reflect cells from EBB, a tissue primarily affected by granuloma formation. Our work provides a foundation for future investigations of MNPs in non-LS and LS sarcoidosis patients, allowing improved stratification to identify patients at risk of developing severe disease and provide early treatment to slow down disease progression.

Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Lepzien, R., Rankin, G., Pourazar, J., Muala, A., Eklund, A., Grunewald, J., Blomberg, A., Smed Sörensen, A. Tags: Sarcoidosis and other granulomatous ILD/DPLD Source Type: research