ETS-1 mRNA and its association with T-BET and Th1 cytokine expression in active pulmonary sarcoidosis

Conclusion: Elevated ETS-1 and T-BET expression in PB of sarcoidosis patients, monitors Th1 cytokines. Our data is suggestive of a regulatory effect of ETS-1 on pro-inflammation. This may have therapeutic implications in sarcoidosis.

Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Sohal, P., Aggarwal, H., Madan, K., Hadda, V., Luthra, K., Mohan, A., Mitra, D. K., Guleria, R. Tags: Sarcoidosis and other granulomatous ILD/DPLD Source Type: research