The new approach to understand the role of IL-15 and BMP proteins in asthma remodelling based on methacholine challenge test evidence.

Conclusions: The higher serum levels of BMP4 and BMP7 in asthmatic patients suggest that these cytokines are involved in inflammation and fibrosis in the airwaysIL-15 increased the expression of BMP4 and BMP7 regardless of the provocative factorIL-15 increased the expression of BMP4 and BMP7 under the influence of methacholine and the potency of the correlation increased in time after the stimulus triggering in the inflammatory reaction
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Allergy and immunology Source Type: research