The activation of NLRP3 inflammasome pathway in COPD is limited in local airways
Conclusion: COPD patients had upregulated level of NLRP3 inflammasome induced IL-1β pathway. This pathway activation represents the innate immune and inflammatory response in the local airway but not a systemic inflammation.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Fu, J.-J., Mao, B., Wang, S.-J., Xiao, W., Li, G.-H., Wu, L.-H. Tags: Airway Cell Biology and Immunopathology Source Type: research
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