Sleep apnea-hypopnea syndrome in elderly obese patients : clinical and functional profiles
Introduction: Sleep apnea-hypopnea syndrome (SAHS) is defined by the repetitive occurrence of brief apneas during sleep. Our objective is to analyze the clinical and functional profiles of SAHS in elderly obese patientsPatients and methods: We performed a retrospective study of 63 elderly obese patients with SAHS. They were sent for body plethysmography. Anthropometric data and personal history were specified. Clinical data (cough, sputum, exercise dyspnea and nocturnal snoring) have been identified. The plethysmographic data were analyzed. Continuous positive pressure (CPAP) treatment was sought.Results: 63 patients were divided into 2 groups according to age: G1 ( 65 years, n = 12). The mean age of G1 was 50 years and of G2 was 72 years. The gender, body mass index (38.2±7.7 vs 37.9±5.58 kg/m²) and active smoking were similar in both groups. The elderly group had higher prevalence of hypertension and diabetes. Sputum and chronic cough were more frequent among elderly patients with respectively (22.2% vs. 63.6% ; p
Authors: Bergland OU, Søraas CL, Larstorp ACK, Halvorsen LV, Hjørnholm U, Hoffman P, Høieggen A, Fadl Elmula FEM Abstract PURPOSE: The blood pressure (BP) lowering effect of renal sympathetic denervation (RDN) in treatment-resistant hypertension shows variation amongst the existing randomised studies. The long-term efficacy and safety of RDN require further investigation. For the first time, we report BP changes and safety up to 7 years after RDN, compared to drug adjustment in the randomised Oslo RDN study. MATERIALS AND METHODS: Patients with treatment-resistant hypertension, defined...
Authors: Zhang W, Xu JZ, Lu XH, Li H, Wang D, Wang JG Abstract PURPOSE: We hypothesise that dietary sodium intake interacts with serum uric acid to influence blood pressure (BP) in children and adolescents. In the present study, we investigated ambulatory BP in relation to hyperuricaemia, dietary sodium intake and their interaction in children and adolescents with hypertension. MATERIALS AND METHODS: A total of 616 study participants were 10-24 years old and had primary hypertension diagnosed after admission in a specialised inpatient ward. Ambulatory BP monitoring was performed during hospitalisat...
CONCLUSIONS: Xyloglucan/gelose plus ORS was effective and safe in treating acute diarrhea in children. PMID: 33028102 [PubMed - as supplied by publisher]
CONCLUSION: The proposed PHARMAC criteria will give access to these important drugs to those people with T2DM who will likely benefit the most. PMID: 33032305 [PubMed - in process]
Authors: Siamashvili M, Davis S Abstract INTRODUCTION: Bromocriptine mesylate quick release (QR) is a dopamine D2 receptor agonist and is the only oral, primarily centrally acting drug that can be used for the treatment of adults with type 2 diabetes. AREAS COVERED: The authors describe current recommendations on the use of bromocriptine mesylate QR. Major efficacy and safety parameters of the late phase trials, including The Cycloset Safety Trial, have been identified and presented. EXPERT OPINION: Efficacy of bromocriptine mesylate QR monotherapy appears to be low but is compensated by favorable safety pr...
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Publication date: Available online 9 October 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Vanda Craveiro, Elisabete Ramos, Joana Araújo
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