Azoles therapeutic drug monitoring and fungal antimicrobial resistance in adults with Cystic Fibrosis

Conclusion: There is high variability in azole TDM in CF adults associated with frequent sub-therapeutic levels and poor drug optimisation. There is a high prevalence of fungal AMR in CF adults with a significant association with sub-therapeutic azole levels.

Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Di Paolo, M., Dave, K., Vijayasingam, A., Sheth, R., Luke, E., Scourfield, A., Nwankwo, L., Schelenz, S., Elborn, J. S., Armstrong-James, D., Shah, A. Tags: Cystic fibrosis Source Type: research