Late Breaking Abstract - Differential effect of intermittent hypoxia and sleep fragmentation in the progression of Alzheimer Disease in a mouse model of obstructive sleep apnea

Conclusions: The results from this work suggest that both IH and SF can participate in the development and progression of AD. However, differences in amyloid deposition and hyperphosporilated Tau emerged between both stimuli, suggesting that SF plays a major role in AD enhancement by OSA.This work was supported by Fundació Marató TV3 (20143231)

Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Almendros, I., Menal, M. J., Gozal, D., Colell, A., Farre, R. Tags: Sleep and control of breathing Source Type: research