Pressure-controlled versus vs. volume-controlled ventilation in patients affected by amyotrophic lateral sclerosis (ALS).

Conclusion: ACV was more effective in reducing abnormal respiratory events than PCV. However, only the latter improved sleep architecture and was preferred by most patients. BaselinePressure modeVolume modepN3 (%)0.0 [0.0-5.1]6.9 [0.4-21.0]1.9 [0.0-8.1]0.03AHI (n/h)5.3 [1.7-24.5]1.3 [0.2-9.7]0.0 [0.0-4.5]<0.001SpO2 mean (%)93.0 [89.7-94.7]94.6 [92.6-96.2]94.3 [92.5-95.4]0.006PtCO2 mean (mmHg)50.0 [46.5-54.7]45.6 [44.0-47.9]46.0 [42.9-48.0]<0.001

Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Crescimanno, G., Canino, M., Greco, F., Marrone, O. Tags: Noninvasive Ventilatory Support Source Type: research