Clinical characteristics and prognosis of infections caused by oxa-48 carbapenemase producing enterobacteriaceae in patients treated with ceftazidime-avibactam

Ceftazidime-avibactam has in vitro activity against Gram-negative bacilli that produce class A, C and some class D β-lactamases, and has been successfully used in the treatment of infections caused by cephalosporin and carbapenem-resistant Enterobacteriaceae. However, actual experience in the treatment of OXA-48 carbapenemase-producing Enterobacteriaceae (CPE) is limited.

Source: International Journal of Antimicrobial Agents - November 21, 2018 Category: Drugs & Pharmacology Authors: C. De la Calle, O. Rodr íguez, L. Morata, F. Marco, C. Cardozo, C. García-Vidal, A. Del Río, C. Feher, M. Pellicé, P. Puerta-Alcalde, J. Mensa, A. Soriano, J.A. Martínez Tags: Short Communication Source Type: research