Diagnostics Are Helping Counter Antimicrobial Resistance, But More Work Is Needed

Antimicrobial resistance (AMR) threats to patient health are becoming more widely recognized and diagnostics manufacturers are making significant progress in combatting the overuse of antibiotics. There is still a lot of work to be done, however. A recent health scare for Rick Bright, Ph.D., director of the Biomedical Advanced Research and Development Authority (BARDA), HHS, the very agency working to combat emerging infectious diseases (EID) and other threats, highlights the lingering risks.  During the 10th Public Meeting of the Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB) in September, Bright recounted his own experience with a multidrug-resistant organism (MDRO). Having contracted the MDRO from a scratch while gardening, he ended up seeking treatment from a number of urgent care clinics before finding one that would treat and culture the wound. According to minutes from the council meeting, Bright described facing potential surgery and even amputation of his thumb. “Costly” rounds of two new antibiotics eventually proved effective, but Bright had to work to track down his culture results, which were positive for methicillin-resistant Staphylococcus aureus (MRSA), he shared.  “The experience demonstrates the need for new standard procedures, such as immediate culturing and point-of-care diagnostics in the emergency department, so providers can prescribe the r...
Source: MDDI - Category: Medical Devices Authors: Tags: IVD Source Type: news

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Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Roumayne L. Ferreira, Brenda C. M. da Silva, Graziela S. Rezende, Rafael Nakamura-Silva, Andr é Pitondo-Silva, Emeline Boni Campanini, Márcia C. A. Brito, Eulália M. L. da Silva, Caio César de Melo Freire, Anderson F. da Cunha, Maria-Cristina da Silva Pranchevicius
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
CANCER symptoms cover a wide range of problems, some which may seem obvious while others are less so. Even simple things like a persistent cough, or frequent heartburn or indigestion could be a sign of some cancers, so it ’s important to monitor any changes to your body, no matter how small. If you suffer from heartburn or indigestion, here’s when to see a GP.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
AbstractBladder cancer is currently considered the most common malignancy of the urinary tract. Thulium laser en bloc resection of bladder tumor (TmLRBT) and plasmakinetic transurethral resection of bladder tumor (PK-TURBT) are two alternative common procedures used in our department to manage patients with primary non-muscle invasive bladder cancer (NMIBC) over the past decade. In this work, the safety and efficacy of TmLRBT were retrospectively compared to those of PK-TURBT in patients with primary NMIBC. From January 2013 to December 2015, 256 patients diagnosed with primary NMIBC were selected for this retrospective st...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
New J. Chem., 2019, Accepted Manuscript DOI: 10.1039/C8NJ06343E, PaperLin Ma, Wenjuan Gao, Xue Han, Fengli Qu, Lian Xia, Rong-Mei Kong Hyaluronidase (HAase) has been reported as a diagnostic and prognostic urinary biomarker for bladder cancer. Simple and sensitive methods capable of quantitative detection of HAase are desired for tumor diagnosis... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
Haiming Liu, Nan Wu, Zhe Zhang, XiaoDan Zhong, Hao Zhang, Hao Guo, Yongzhan Nie, Yuanning Liu
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Patients receiving new kidneys and livers must take damaging anti-rejection drugs for the rest of their lives. Now researchers hope to train the immune system instead of just tamping it down.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Transplants Kidneys Organ Donation Liver Immune System Drugs (Pharmaceuticals) Dana-Farber Cancer Institute Massachusetts General Hospital University of Pittsburgh Medical Center Pittsburgh (Pa) Source Type: news
We report the case of a 60-year-old female with a history of chronic low back and legs pain secondary to L4 and L5 laminectomies posterior arthrodesis and fusion.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research
This study aimed at exploring the effects of tDCS on negative emotion regulation as it pertains to ADHD related symptoms, which could potentially provide support for the use of the tDCS as an alternative treatment for ADHD.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research
Vagal nerve stimulation is gaining recognition as an important therapeutic approach especially for non-communicable diseases such as cardiovascular disease (CVD), Depression, Fibromyalgia, Arthritis, Type 2 Diabetes, Alzheimer, and certain types of cancer. In turn, decreased vagal tone its implicated in the prognosis of a wide range of diseases. Afferent vagal stimulation seems to have the key to reset certain pathophysiological states of the body leading to health improvement by reshaping neural networks.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research
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