Depletion of MicroRNA-373 Represses the Replication of Hepatitis C Virus via Activation of Type 1 Interferon Response by Targeting IRF5.

CONCLUSION: miR-373 abrogation reduced HCV replication via activation of type 1 IFN responses by targeting IRF5 in JFH1-infected Huh 7.5 cells, suggesting a promising therapeutic for treating HCV infection. PMID: 30450852 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30450852?dopt=Abstract

Source: Yonsei Medical Journal - November 21, 2018 Category: Universities & Medical Training Authors: Gong W, Guo X, Zhang Y Tags: Yonsei Med J Source Type: research