Opioids Are In the Spotlight. But Meth Hospitalizations Are Surging

The number of people hospitalized because of amphetamine use is skyrocketing in the United States, but the resurgence of the drug largely has been overshadowed by the nation’s intense focus on opioids. Amphetamine-related hospitalizations jumped by about 245% from 2008 to 2015, according to a recent study in the Journal of the American Medical Association. That dwarfs the rise in hospitalizations from other drugs, such as opioids, which were up by about 46%. The most significant increases were in Western states. The surge in hospitalizations and deaths due to amphetamines “is just totally off the radar,” said Jane Maxwell, an addiction researcher. “Nobody is paying attention.” Doctors see evidence of the drug’s comeback in emergency departments, where patients arrive agitated, paranoid and aggressive. Paramedics and police officers see it on the streets, where suspects’ heart rates are so high that they need to be taken to the hospital for medical clearance before being booked into jail. And medical examiners see it in the morgue, where in a few states, such as Texas and Colorado, overdoses from meth have surpassed those from the opioid heroin. Amphetamines are stimulant drugs, which are both legally prescribed to treat attention deficit hyperactivity disorder and produced illegally into methamphetamine. Most of the hospitalizations in the study are believed to be due to methamphetamine use. Commonly known as crystal meth, methamphe...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized public health Source Type: news

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This study sought to investigate the relationship between galectin-3 (Gal-3), myocardial fibrosis (MF) and outcomes in acute heart failure. Materials &methods: The single-nucleotide polymorphisms (SNPs) of LGALS3 at rs4644 and rs4652, plasma Gal-3 level, MF and major adverse events (MAEs) were obtained. Results: There was no significant difference in MAEs when categorizing patients by the LGALS3 SNPs at rs4644 and rs4652. The circulating Gal-3 was related to the degree of MF (p
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research
CONCLUSIONS: The F-V relationship assessed during both specific (SSKT) and nonspecific upper-body tasks (bench press and bench pull) may distinguish between kayakers specialized in different distances. PMID: 32942255 [PubMed - as supplied by publisher]
Source: International Journal of Sports Physiology and Performance - Category: Sports Medicine Tags: Int J Sports Physiol Perform Source Type: research
The objectives of this article are the following: 1) to examine fibromyalgia and somatic symptom disorder analogy. 2) to discuss stress-evoked neuropathic pain sexual dimorphism, and 3) to propose a neuropathic pathogenesis that may explain how stressed women could develop fibromyalgia. Recent research demonstrates a clear link between fibromyalgia and small fibre neuropathy. Dorsal root ganglia contain the small nerve fibre nuclei. In rodents, physical, chemical, or environmental stressors lead to dorsal root ganglia phenotypic changes and to hyperalgesia. This phenomenon is much more frequent in females. Prolactin, oestr...
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Authors: Bolek EC, Kaya Akca U, Sari A, Sag E, Demir S, Kilic L, Sener YZ, Aykan HH, Kaya EB, Bilginer Y, Akdogan A, Kiraz S, Karadag O, Ozen S Abstract OBJECTIVES: Takayasu's arteritis (TAK) is a chronic vasculitis, affecting predominantly the aorta and/or its major branches. The aim of this study was to compare the differences between childhood and adult onset TAK. METHODS: We retrospectively evaluated 179 TAK patients followed between August 2005 and July 2019. Demographic characteristics, laboratory features, disease activity, echocardiographic data at diagnosis and treatment regimens in the disease course ...
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Conclusions: Standing balance enhancement (higher equilibrium score/better balance) depends on the neuropsychological process targeted and the sensory input available post-stroke. Cognitive dual-task interference emerged for the verbal fluency test during the most attention demanding sensory condition. Cognitive tests that enhance standing balance should be considered in assessments and interventions to evaluate and improve dual-tasking post-stroke. Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1, available at: http://links.lww.com/JNPT/A321).
Source: Journal of Neurologic Physical Therapy - Category: Physiotherapy Tags: Research Articles Source Type: research
Conclusions: The results indicate that fall risk measures within the ICF domains—body, structure, and function (dynamic gait stability and hip extensor strength) and activity limitation (TUG)—could provide a sensitive laboratory-induced slip-fall prediction model in PwCS. Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1, available at: http://links.lww.com/JNPT/A323).
Source: Journal of Neurologic Physical Therapy - Category: Physiotherapy Tags: Research Articles Source Type: research
Conclusions: Telephone-based administration of the ABILHAND is valid for the assessment of manual ability after stroke. Clinicians and researchers may use the ABILHAND for monitoring manual ability in persons with stroke and/or screening potential research participants. Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1, http://links.lww.com/JNPT/A318).
Source: Journal of Neurologic Physical Therapy - Category: Physiotherapy Tags: Research Articles Source Type: research
Authors: Pozzi M, Bertella S, Gatti E, Peeters GGAM, Carnovale C, Zambrano S, Nobile M Abstract INTRODUCTION: Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder affecting up to 5.29% of children and 2.5% of adults depending on the country considered. Current pharmacological treatments for ADHD are based on stimulant or non-stimulant medications, targeting dopaminergic and noradrenergic systems in the frontal cortex and dopaminergic system in the basal ganglia. These drugs are effective and safe for the majority of patients, whereas about 20% of treated patients do not tolerate current ...
Source: Expert Opinion on Emerging Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Emerg Drugs Source Type: research
Chem. Commun., 2020, Accepted Manuscript DOI: 10.1039/D0CC04999A, CommunicationChristina McConville, Yunwen Tao, Hayden Evans, Benjamin A. Trump, Jonathan B. Lefton, Wenqian Xu, Andrey Yakovenko, Elfi Kraka, Craig M Brown, Tom če Runčevski Benzene and acetonitrile are two of the most commonly used solvents found in almost every chemical laboratory. Titan is one other place in the Solar system that has large amounts... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research
Number of cases worldwide passes 30 million; Victoria announces 21 new Covid-19 cases and seven more deaths; UK faces possible second national lockdown. Follow all the developmentsMutant virus: should we be worried that Sars-CoV-2 is changing ?UK entering second wave of virus, Johnson warns‘Shocking’: Trump under fire from ex-adviser for Covid failures5.31amBSTThe Victorian Department of Health and Human Services has put out some more information on the latest case numbers today.The 21 cases is the lowest number of new cases since 24 June.Of the 834 current active cases in Victoria:5.12amBSTThe Australian minis...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak Infectious diseases Science World news Source Type: news
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