Using a muscle pump activator device to stimulate healing for non ‐healing lower leg wounds in long‐term care residents

The objective of this LTC Innovation pilot was to test the value of a promising new neuromuscular stimulation device in elevating the experience and satisfa ction of the residents, engaging and empowering the nursing staff, and improving healing and/or reducing costs. Small, wireless, and worn at the knee, this muscle pump activator is self‐contained, wearable, and battery‐powered to increase lower‐leg blood circulation (up to 60% of that achieved by walking). It has no wires, weighs just 10 g, and is easy to use. Nurses in four LTC homes identified residents with non‐healing lower leg wounds. Consent was obtained, and on‐site training was delivered. Eleven residents were recruited. Only seven met the inclusion criteria for venous/mixed or diabetic foot ulcers. Of the seven who met the criteria and were adherent with best practices and the muscle pump activator, four healed 100%, and one healed 90%. Two patients with other aetiologies, who were also adherent, healed. All adherent residents had an average weekly decrease in wound si ze of 9.75% and were extremely happy with the results. Three residents who were non‐adherent had a 9.25% increase in wound size per week. One patient with diabetic foot ulcers developed skin changes at the end of life and passed away. Nursing staff and cognisant residents can easily adjust the pul se of muscle pump activator, and application and removal are simple. Most residents feel engaged with the therapy “because they feel it...
Source: International Wound Journal - Category: Surgery Authors: Tags: ORIGINAL ARTICLE Source Type: research

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Purpose of review The current review addresses one of the most common neurological disorders, diabetic polyneuropathy (DPN). DPN is debilitating, irreversible and dwarfs the prevalence of most other chronic disorders of the nervous system. Its complications include foot ulceration, amputation, falling and intractable neuropathic pain. Moreover, tight control of hyperglycemia reduces the incidence of DPN in type 1 diabetes mellitus but its role in type 2 diabetes mellitus is less clear. Recent findings New therapeutic options to reverse the development of DPN or its associated pain have been proposed but none have sign...
Source: Current Opinion in Neurology - Category: Neurology Tags: PERIPHERAL NERVE AND NEURO-MUSCULAR JUNCTION DISEASE: Edited by Mary M. Reilly Source Type: research
Abstract There are>12 million patients with peripheral artery disease in the United States. The most severe form of peripheral artery disease is critical limb ischemia (CLI). The diagnosis and management of CLI is often challenging. Ethnic differences in comorbidities and presentation of CLI exist. Compared with white patients, black and Hispanic patients have higher prevalence rates of diabetes mellitus and chronic renal disease and are more likely to present with gangrene, whereas white patients are more likely to present with ulcers and rest pain. A thorough evaluation of limb perfusion is important in the d...
Source: Circulation - Category: Cardiology Authors: Tags: Circulation Source Type: research
ConclusionsAMX ameliorated pain and extent of a chronic diabetic ulcer. The effect could be ascribed to angiogenesis and epithelium stimulation that was confirmed in in vitro. Multiple wound healing-involved proteins were detected but further studies are needed to assess their specific role.
Source: Wound Medicine - Category: General Medicine Source Type: research
In the minutes after block 4 of the nuclear power plant in Chernobyl exploded, no one knew that they are experiencing a disaster that never happened anywhere before on planet Earth. The public health, environmental, and even the socio-political consequences were disastrous and we can still experience the negative impacts. That’s why we posed the question of what public health authorities, as well as individuals, can do to mitigate the consequences of radiation exposure, and what digital technologies are available for radiation detection. In this respect, after our investigations, it even turned out that it would be b...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine Space Medicine astronautics chernobyl disaster fiction Health Healthcare Innovation mars nuclear power plant public health radiation radiation exposure radiation protection technology Source Type: blogs
Conclusions The clinical trials discussed here, which include several trials investigating novel therapeutic targets, demonstrate that translational research in pemphigus and pemphigoid is a fast-growing field. We thus expect that several novel treatments will be shortly available for the treatment of pemphigus and pemphigoid patients. Given the high, and thus far unmet, medical need in this field (110), this is highly encouraging and will hopefully improve the quality of life of the affected patients. In addition to the compounds and targets described here, several new targets have been recently identified in preclinical...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Conclusion: Our findings describe the most reported risk factors for preventability of oral anticoagulant-induced bleedings. These factors may be useful for targeting interventions to improve pharmacovigilance activities in our regional territory and to reduce the burden of medication errors and inappropriate prescription. Introduction Oral anticoagulant therapy is widely used for the prevention of stroke and systemic embolism in patients with atrial fibrillation, or for the prevention and treatment of deep vein thrombosis and pulmonary embolism (Raj et al., 1994; Monaco et al., 2017). Oral anticoagulants can be di...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusion This paper summarizes the current findings regarding the anti-colitis activity of plant-derived alkaloids and shows how these alkaloids exhibit significant and beneficial effects in alleviating colonic inflammation. These natural alkaloids are not only promising agents for IBD treatment but are also components for developing new wonder drugs. However, the underlying molecular mechanisms or toxicological evaluation of most plant-derived alkaloids still require much scientific research, and their actual efficacies for IBD patients have not been verified well in field research. Thus, further clinical trials to elu...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
  When traditional treatments fail to heal wounds, many doctors look to modern alternatives to help patients recover. Regenerative medicine is one of the most recent developments to become a worthy treatment alternative. Here’s an overview of regenerative medicine and its role in wound care: What is regenerative medicine? The National Institutes of Health defines regenerative medicine as the process of creating living, functional tissues to repair or replace lost tissue or organ function. Through regeneration, replacement and rejuvenation, regenerative-medicine techniques work with the body’s nat...
Source: Advanced Tissue - Category: Dermatology Authors: Tags: Wound Care Wound healing Source Type: news
Publication date: Available online 30 March 2019Source: Trends in Endocrinology &MetabolismAuthor(s): Christian Herder, Michael Roden, Dan ZieglerThe most prevalent chronic complications of diabetes are diabetic neuropathies, among which distal sensorimotor polyneuropathy (DSPN) and cardiovascular autonomic neuropathy (CAN) are the best studied. Their major clinical sequelae such as foot ulcers, neuropathic pain, and orthostatic hypotension are associated with lower quality of life and increased risk of mortality. Here we discuss the recent insights into DSPN and CAN focusing on two prospective cohorts; that is, the Ge...
Source: Trends in Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Abstract The most prevalent chronic complications of diabetes are diabetic neuropathies, among which distal sensorimotor polyneuropathy (DSPN) and cardiovascular autonomic neuropathy (CAN) are the best studied. Their major clinical sequelae such as foot ulcers, neuropathic pain, and orthostatic hypotension are associated with lower quality of life and increased risk of mortality. Here we discuss the recent insights into DSPN and CAN focusing on two prospective cohorts; that is, the German Diabetes Study (GDS) including recent-onset diabetes patients and the population-based Cooperative Health Research in the Regio...
Source: Trends in Endocrinology and Metabolism: TEM - Category: Endocrinology Authors: Tags: Trends Endocrinol Metab Source Type: research
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