Prognostic Value of HER-2/neu Gene Amplification in Epithelial Ovarian Carcinoma

ConclusionsThe introduction of HER2-directed therapies has dramatically influenced the outcome of patients with HER2 positive breast and gastric/gastroesophageal cancers. The present study findings provided that HER-2/neu expression in patients with OC has an adverse impact on the PFS. Therefore, our results show that the decision algorithm usually used in breast cancer by HER2 may be appropriate in ovarian cancer.
Source: The Journal of Obstetrics and Gynecology of India - Category: OBGYN Source Type: research