Quercus Brantii Lindl. Vaginal Cream versus Placebo on Bacterial Vaginosis: a Randomized Clinical Trial

Publication date: Available online 20 November 2018Source: Journal of Herbal MedicineAuthor(s): Atefeh Zare, Zeinab Moshfeghy, Mohammad M. Zarshenas, Bahia Namavar jahromi, Marzieh Akbarzadeh, Mehrab SayadiAbstractThe current study aimed to compare the effects of Quercus brantii Lindl. vaginal cream in combination with metronidazole tablet on Bacterial Vaginosis (BV). A total of 176 eligible women with BV were enrolled. Diagnosis was based on having 3 or more signs described by Amsel’s criteria and a Nugent score of ≥7. Symptoms were evaluated before and after treatments. Participants were divided into two experimental groups based on permuted-block randomization. Group A (n = 89) received 500 mg of metronidazole tablet every 12 hours as well as a vaginal placebo cream. Group B (n = 87) received 500 mg of the same tablet with a vaginal Quercus brantii cream. Seven to 10 days after the treatments, Amsel’s criteria, Nugent scores, and the clinical symptoms were assessed again. The data were analyzed via chi-square, independent, and paired t-tests using SPSS software. After the treatments, significant differences were observed between the two groups in terms of malodours discharge and Nugent score. Based on the total cure, 50.0% of the patients in group A and 73.8% of those in group B were found to have been treated when assessed by both Nugent score and Amsel’s criteria. The findings suggested the better results of metronidazole+Quercus brantii vaginal cre...
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research