Disulphide Bridges in Surfactant Protein B Analogues Affect Their Activity in Synthetic Surfactant Preparations

Conclusion: The helix-loop-helix SP-B analogues tested in this study require the presence of 2 disulphide bridges for optimal activity in a rabbit RDS model.Neonatology 2019;115:134 –141
Source: Neonatology - Category: Perinatology & Neonatology Source Type: research