Hydrogen sulfide ameliorated lipopolysaccharide-induced acute lung injury by inhibiting autophagy through PI3K/Akt/mTOR pathway in mice.

CONCLUSION: Autophagy inhibition through PI3K/Akt/mTOR pathway was involved in H2S prevention of LPS-induced ALI in mice.
PMID: 30448177 [PubMed - as supplied by publisher]

Source: Biochemical and Biophysical Research communications - November 15, 2018 Category: Biochemistry Authors: Xu X, Li H, Gong Y, Zheng H, Zhao D Tags: Biochem Biophys Res Commun Source Type: research