A chitinase-like protein from Sarcoptes scabiei as a candidate anti-mite vaccine that contributes to immune protection in rabbits

Scabies is caused by Sarcoptes scabiei burrowing into the stratum corneum of the host ’s skin and is detrimental to the health of humans and animals. Vaccines are an attractive alternative to replace the acaricide...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research

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Scabies, a parasitic disease of the skin, is a major public health problem, largely affecting children. Scabies is often complicated by impetigo which can result in serious complications including invasive inf...
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Research article Source Type: research
Abstract Scabies is highly prevalent worldwide with a significant DALYs global burden, affecting 100-200 million people annually.1 In hyper-endemic tropical regions, the link with secondary bacterial infections is increasingly recognised. Group A streptococcal and staphylococcal pyoderma can cause bacteraemia,2 glomerulonephritis and acute rheumatic fever potentially leading to rheumatic heart disease. Current scabies treatments are few in number and suboptimal. As neuroinhibitors they are expected to kill motile stages but could be poorly ovicidal. Emerging drug resistances in the parasites are a further concern....
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
Abstract Scabies is a common skin disease with an estimated worldwide incidence of 200 million people infected per year. Its morbidity and mortality is principally due to secondary bacterial infections, a link now well recognized and prompting the recent inclusion of this disease-complex in the WHO list of neglected tropical diseases. The few treatments available are poorly effective against Sarcoptes scabiei eggs and appear to induce resistance in the parasite. An ideal alternative would be a single-dose regimen that kills all developmental stages, including eggs. Drugs used in the veterinary field and applied to...
Source: Trends in Parasitology - Category: Parasitology Authors: Tags: Trends Parasitol Source Type: research
(Murdoch Childrens Research Institute) Results of a two-year update of the world's first comparative trial of mass drug administration against scabies, show that the infection rate is still significantly down. The latest findings are published today in the New England Journal of Medicine.In 2012, the Murdoch Children's Research Institute, the Kirby Institute and the Fiji Ministry for Health, treated almost everyone on a remote Fijian island (716 people) with the oral anti-parasitic drug ivermectin.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
Publication date: Available online 13 June 2019Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Kevin D. Niedringhaus, Justin D. Brown, Kellyn M. Sweeley, Michael J. YabsleyAbstractThe “itch mite” or “mange mite”, Sarcoptes scabiei, causes scabies in humans and sarcoptic mange in domestic and free-ranging animals. This mite has a wide host range due to its ability to adapt to new hosts and has been spread across the globe presumably through human expansion. While disease caused by S. scabiei has been very well-studied in humans and domestic animals, there are still nu...
Source: International Journal for Parasitology: Parasites and Wildlife - Category: Parasitology Source Type: research
(Murdoch Childrens Research Institute) An alignment of researchers, health ministries and the World Health Organization has outlined the steps to develop a global program to control scabies -- the parasitic disease affecting 450 million people annually in mainly low-income countries. The paper published in The Lancet journal was led by Murdoch Children's Research Institute, in collaboration with the International Alliance for the Control of Scabies, the World Health Organization, researchers and the Ethiopian, Solomon Islands and Fijian Health Ministries.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Publication date: Available online 6 June 2019Source: The LancetAuthor(s): Daniel Engelman, Paul T Cantey, Michael Marks, Anthony W Solomon, Aileen Y Chang, Olivier Chosidow, Wendemagegn Enbiale, Dirk Engels, Roderick J Hay, David Hendrickx, Peter J Hotez, John M Kaldor, Mike Kama, Charles D Mackenzie, James S McCarthy, Diana L Martin, Birhan Mengistu, Toby Maurer, Nebiyu Negussu, Lucia RomaniSummaryScabies is a parasitic disease of the skin that disproportionately affects disadvantaged populations. The disease causes considerable morbidity and leads to severe bacterial infection and immune-mediated disease. Scientific adv...
Source: The Lancet - Category: General Medicine Source Type: research
A skin infection occurs when parasites, fungi, or germs such as bacteria break into the skin. Some examples of these invaders include scabies, the herpes virus, and lice. Here, learn more about skin infections and what they look like.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Dermatology Source Type: news
Scabies is an infestation of the skin by tiny parasitic mites. On the penis, scabies can cause crusty, blister-like sores and intense itching that may get worse at night. Scabies mites spread through close, prolonged contact between people, such as during sex. Learn more about scabies on the penis here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Sexual Health / STDs Source Type: news
Answer toParasite Case of the Week 531:Sarcoptes scabei,var. hominis, the human " itch " mite. Seen here are mites, eggs and fecal pellets (scybala).Old one nicely described the biology and morphology of these arthropods:Sarcoptes scabeioccur in a number of host species. Primarily in swine here in Minnesota but occasionally in humans. The male mites range in size from 213-285 μm long by 162-240 μm wide and the female mites range from 300-504 μm long to 230-420 μm wide.Sarcoptesare round to ovoid when viewed from the back; when viewed from the side they are ventrally flattened and dorsally rounded (sim...
Source: Creepy Dreadful Wonderful Parasites - Category: Parasitology Source Type: blogs
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