Healing of autoimmune hepatitis associated with hepatitis C virus infection treated with direct-acting antivirals.

Healing of autoimmune hepatitis associated with hepatitis C virus infection treated with direct-acting antivirals. Rev Esp Enferm Dig. 2018 Nov 19;110: Authors: López Couceiro L, Gómez Domínguez E, Muñoz Gómez R, Castellano Tortajada G, Ibarrola de Andrés C, Fernández Vázquez I Abstract The use of direct-acting antivirals (DAA) for the hepatitis C virus (HCV) has yielded a significant improvement in the treatment of autoimmune hepatitis (AIH) associated with HCV infection. Interferon was the cornerstone of HCV therapy before the introduction of these agents into the clinical practice. Herein, we report the case of an HCV-infected patient who developed an interferon-induced AIH and since then, has received immunosuppressive therapy. Administration of DAA resulted in a sustained virologic response (SVR) and clinical AIH remission which allowed a discontinuation of immunosuppressive treatment. PMID: 30449122 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research