LY294002, a PI3K pathway inhibitor, prevents leptin ‐induced adverse effects on spermatozoa in Sprague‐Dawley rats

In conclusion, LY294002 prevents leptin‐induced changes in rat sperm parameters, suggesting the potential role of the PI3K signalling pathway in the adverse effects of leptin on sperm param eters.

Source: Andrologia - November 19, 2018 Category: Urology & Nephrology Authors: Amir Hafidz Md Mokhtar, Ifrah Alam Malik, Noor Azean Anis Abd Aziz, Fayez A. Almabhouh, Damayanthi Durairajanayagam, Harbindar Jeet Singh Tags: ORIGINAL ARTICLE Source Type: research