Grand Round: Autoimmune Hepatitis

Autoimmune hepatitis (AIH) is a corticosteroid responsive, autoimmune liver disease arising consequent to immunogenetic and environmental risk factors. The clinical course reflects relapsing and remitting, hepatocyte targeted, immunologic damage, countered by reparative responses to cell injury. Appropriate and timely immunosuppressive therapy drives disease into remission, albeit accompanied by inevitable side effects. Many challenges faced in the clinic reflect practice that must capture a heterogeneous disease presentation, course, and treatment response, as well as treatment tolerability.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Grand Rounds Source Type: research