Delayed Diagnosis of Cystic Fibrosis in a 62 Year Old Female Leading to Bilateral Lung Transplant

Delayed Diagnosis of Cystic Fibrosis in a 62 Year Old Female Leading to Bilateral Lung TransplantConference abstracts
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news

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Azole-resistant Aspergillus fumigatus (ARAF) has been reported in the domestic environment of patients at risk for aspergillosis. Here, we assessed the mother's and father's homes of an 18-year-old cystic fibrosis patient harbouring chronic colonisation with H285Y CYP51A azole-resistant isolate, in order to explore the link between environmental exposure and ARAF infection. In one dwelling, a very high overall contamination level was found (710 –7.240 CFU/m3), with a predominance of A. fumigatus (640–6.490 CFU/m3), and ARAF showing the TR34/L98H mutation was isolated.
Source: Journal of Cystic Fibrosis - Category: Respiratory Medicine Authors: Tags: Short Communication Source Type: research
Progressive lung injury in Cystic Fibrosis (CF) patients can lead to chronic colonization with bacteria and fungi. Fungal colonization is obtained from the environment which necessitates locally performed epidemiology studies. We prospectively analyzed respiratory samples of CF patients during a 3-year period, using a uniform fungal culture protocol, focusing on filamentous fungi and azole resistance in Aspergillus fumigatus.
Source: Journal of Cystic Fibrosis - Category: Respiratory Medicine Authors: Source Type: research
Conference abstracts
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Conference abstracts
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Conference abstracts
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Conference abstracts
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Conference abstracts
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Conference abstracts
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Introduction: International guidelines suggest a limited bundle of tests to investigate Bx etiology. We aimed to evaluate an extensive bundle performed on every patient to increase the chances to identify a treatable etiology.Methods: A prospective, observational study was conducted at Policlinico Hospital in Milan, Italy, from 2014 to 2017. All consecutive adults with Bx underwent the following tests: CBC, Aspergillus IgG and IgE, serum electrophoresis, sweat test and genetics for cystic fibrosis, immunoglobulins, IgG subclasses, lymphocytes subsets, nasal NO, autoantibodies, serum level and genetics for alpha1-antitrypsi...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Clinical Problems Source Type: research
Conclusion: In our data, post TB bronchiectasis remained the most common cause of non-CF bronchiectasis, Pseudomonas is the most common pathogen, obstructive pattern of spirometry is found in majority and hemoptysis is the most frequent complication.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Respiratory infections Source Type: research
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