VCAM-1+ macrophages guide the homing of HSPCs to a vascular niche

VCAM-1+ macrophages guide the homing of HSPCs to a vascular nicheVCAM-1⁺ macrophages guide the homing of HSPCs to a vascular niche, Published online: 19 November 2018; doi:10.1038/s41586-018-0709-7In zebrafish embryogenesis, nascent haematopoietic stem and progenitor cells (HSPCs), homing to a vascular niche for retention, are ushered by patrolling and guiding macrophages through integrin-mediated cell-cell recognition.

Source: Nature AOP - November 19, 2018 Category: Research Authors: Dantong Li Wenzhi Xue Mei Li Mei Dong Jianwei Wang Xianda Wang Xiyue Li Kai Chen Wenjuan Zhang Shuang Wu Yingqi Zhang Lei Gao Yujie Chen Jianfeng Chen Bo O. Zhou Yi Zhou Xuebiao Yao Lin Li Dianqing Wu Weijun Pan Source Type: research