Characterization of aged rat vocal fold fibroblasts

ConclusionsThe following possible characteristics of aged VFFs were implied: long duration of mitosis, increased myofibroblast population size with certain dysfunctions, reduced type I collagen turnover, and correlation between α‐SMA expression and type I collagen metabolism. Further investigations of these features will help to clarify presbyphonia's pathology and establish treatment strategies.Level of EvidenceNALaryngoscope, 2018

Source: The Laryngoscope - November 19, 2018 Category: ENT & OMF Authors: Yoshitaka Kawai, Yo Kishimoto, Tohru Sogami, Ryo Suzuki, Takuya Tsuji, Nao Hiwatashi, Ichiro Tateya, Shin ‐Ichi Kanemaru, Tatsuo Nakamura, Koichi Omori, Shigeru Hirano Tags: Laryngology Source Type: research