Comparative study of βs-lactam de-labeling on the frequency of peri-operative vancomycin use
Vancomycin is the antibiotic of choice in β-lactam allergic adults undergoing surgical antibiotic prophylaxis. Because it is a suboptimal option, in 2015 a pre-operative drug allergy screening program began at the Montreal General Hospital (MGH). It de-labeled 94 % of patients evaluated, reducing vancomycin use to 3 %. To validate the prog ram effectiveness a prospective study comparing the Royal Victoria Hospital (RVH), which lacked de-labeling was undertaken.The aim of the study was to determine the effect of a de-labeling program on vancomycin use.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Y. Moussa, J. Shuster, G. Matte, A. Sullivan, C. Mavridis, M. Ben-Shoshan, U. Pfeiffer, G. Baldini, R. Bondy, F. Carli, C. Tsoukas Tags: A102 Source Type: research